These efforts have been successful, and Dr. Biris’ university spinout venture NuShores received a fourth award in FY20 by the U.S. Army’s Medical Research and Development Command’s Clinical and Rehabilitative Research Program (CRMRP) via an Other Transaction Agreement (OTA) competitively awarded through the Medical Technology Enterprise Consortium (MTEC). This transition of the initial NuCressTM manufacturing process from the JWMRP to the MTEC focuses on the optimization of the manufacturing process by investigating multiple and consecutive iterations of automation to improve quality, cost and efficiency. The deliverable is to demonstrate the feasibility of producing the NuCressTM bone void filler scaffold by a fully automated, intelligent production system with real-time in-process quality monitoring and control.